In this chapter, we propose a general model of how the human mental apparatus—as we conceive of it in psychoanalysis—might be represented in the tissues of the brain. Since this is a first approach at something unknown, it goes without saying that our proposals are subject to substantial revision. The hypotheses that we present are based on a small amount of empirical data, derived from psychoanalytic investigations of 35 patients with localized cerebral lesions, 12 of whom we described in part II. In all likelihood, our perspective on these problems will alter radically as we continue to test our hypotheses against clinical reality. However, excessive caution should not prevent from us pausing at this point to gain a first, schematic perspective on what our efforts have yielded thus far. The aim of a preliminary overview of this sort is for us to take our bearings for the research that still needs