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Edward Bernard Klein was born on May 21, 1931 in Brooklyn, New York, to Jewish immigrants from Russia, Iris and Manuel Klein. After serving in the Army during the Korean Conflict, he used the GI Bill to attend the University of Michigan in Ann Arbor, earning his BA in sociology and psychology, and his PhD in psychology from Columbia University.
Dr Klein began his career at the Veterans' Administration Hospital and Connecticut Mental Health Center (CMHC) in New Haven. While at the CMHC, he became involved in the community psychology movement, which influenced themes throughout his career. As a faculty member at Yale University in the mid-1960s, his early research focused on schizophrenia. As Assistant and Associate Professor at Yale, he joined the Center for Education in Groups and Organizations,