The author addresses the issue of hatred by linking it to the human difficulty of recognising the fundamental dependence of one’s condition. Refusal to accept dependence on the other leads to hating and rejecting the other, and thus to depriving oneself of what one fundamentally expects of the other. The author illustrates this clinically from his practice, which focuses on hatred within a couple, while distinguishing different situations and the consequences for the conduct of the treatment. He compares each case with certain novels by Georges Simenon, which are also centred on hatred within the couple. This makes it possible, starting from the passionate, loving and murderous dimension, to make a link between the role of literary fiction, the notion of the “destroyed-found” proposed by René Roussillon, and the specific challenge of the treatment.